sotorasib will reduce the extent or effect of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. If use is unavoidable, make reference to the prescribing information and facts in the CYP3A4 substrate for dosage modifications
In only one-night, double-blind, parallel-team trial comparing estazolam 2 mg and placebo in people admitted for elective surgical procedures and requiring sleep drugs, estazolam was remarkable to placebo in subjective steps of slumber induction and servicing.
duvelisib will raise the degree or influence of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Intently. Coadministration with duvelisib boosts AUC of a delicate CYP3A4 substrate which can raise the hazard of toxicities of these medicine.
You'll be able to establish an habit Even when you consider estazolam particularly as prescribed by your Health care supplier.
Voxelotor will increase systemic exposure of sensitive CYP3A4 substrates. Prevent coadministration with sensitive CYP3A4 substrates by using a narrow therapeutic index. Consider dose reduction with the delicate CYP3A4 substrate(s) if unable to keep away from.
Medicine which have move therapy associated with Each and every prescription. This restriction normally needs that specified standards be fulfilled previous to acceptance for the prescription.
fosamprenavir will raise the amount or result of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
If estazolam is supplied concomitantly with other medicine performing on the central nervous technique, very careful consideration must be specified towards the pharmacology of all agents.
ribociclib will improve the degree or effect of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
talquetamab will boost the amount or influence of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Trazodone Warning/Keep an eye on. Talquetamab will cause cytokine launch syndrome (CRS) that will suppress action of CYP enzymes, resulting in elevated publicity of CYP substrates.
itraconazole will boost the stage or impact of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Each medicine will improve QT interval
Prevent having this medication and call your treatment workforce right away if you find out you have performed pursuits such as this.
verapamil will increase the level or impact of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
enzalutamide will reduce the level or impact of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.